Deals on vacations and trips to Southeast Missouri

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Southeast Missouri flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

2 out of 5
Price was $472, price is now $434 per person
$434
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Oklahoma City (OKC) to St. Louis (STL)
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A snack bar/deli is provided and the front desk is staffed around-the-clock.
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

3 out of 5
Creve Coeur
Price was $650, price is now $614 per person
$614
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Oklahoma City (OKC) to St. Louis (STL)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express check-out. Self parking, a coffee shop, and a snack bar/deli are also offered.
Staybridge Suites St Louis - Westport by IHG

Staybridge Suites St Louis - Westport by IHG

3 out of 5
Westport
Price was $679, price is now $653 per person
$653
per person
Sep 18 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to St. Louis (STL)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. There's a gym on site, and laundry facilities and free newspapers are also offered.
Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG

3 out of 5
Price was $607, price is now $590 per person
$590
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Oklahoma City (OKC) to St. Louis (STL)
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, conference center, and conference space. Enjoy the seasonal outdoor pool and perks like free self parking.
Holiday Inn Express & Suites St Louis Airport by IHG

Holiday Inn Express & Suites St Louis Airport by IHG

2.5 out of 5
Woodson Terrace
Price was $662, price is now $645 per person
$645
per person
Sep 18 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Providence (PVD) to St. Louis (STL)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and free airport drop-off. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's a gym on site, and a 24-hour front desk and express check-in are also provided.

Top Southeast Missouri hotels deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $113 total per night
$113 total
Aug 13 - Aug 14
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
$58 nightly
The price is $63 total per night
$63 total
Aug 15 - Aug 16
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $113 total per night
$113 total
Aug 12 - Aug 13
Total with taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. Relax with a drink at one of the 2 bars/lounges and enjoy perks like free self parking.
Parking included
Free WiFi
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $128 total per night
$128 total
Aug 12 - Aug 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Baymont by Wyndham Festus

Baymont by Wyndham Festus

3 out of 5
1200 W. Gannon Drive Festus MO
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $72 total per night
$72 total
Aug 26 - Aug 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Families will appreciate the arcade/game room and barbecue grills. Relax with a drink at the bar/lounge and enjoy free perks like continental breakfast and free self parking.
Pool
Breakfast included
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

3 out of 5
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $112 total per night
$112 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southeast Missouri attractions

A large, reddish-brown rock formation with a smooth, rounded surface and a unique, intertwined shape.
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

9.6/10 (98 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
See properties

Frequently asked questions

How much are vacation packages to Southeast Missouri?
Packages, which include flights and hotels in Southeast Missouri, start at just $434. Make your travel dreams a reality and book your dream trip with Travelocity today.
Where can I get the best vacation package deals for Southeast Missouri?
There are fantastic Southeast Missouri package deals to score with Travelocity. Did you know we partner with as many as 400 airlines and 1,000,000 properties around the globe? Keep that in mind when you're ready to cross another place off your travel bucket list.
Why should I book my Southeast Missouri vacation package via Travelocity?
From incredible destinations to thrilling experiences, we have everything you need to satisfy your love for travel. Our 24/7 customer care will also ensure you're being taken care of before, during and after your trip. And don't panic if you notice a lower price on your booking, we'll match it. That's our Price Match Guarantee.
Will I save money on my Southeast Missouri car rental if I bundle it with my hotel or flight?
Absolutely. And our Southeast Missouri vacation packages are the perfect way to do it. With just a few clicks you can save cash as well as time by combining your bookings. Collect the keys to your rental car then set your own course. Looking for things to do? Add some tours or experiences to your package and make savings on those too.
Which airport is best for Southeast Missouri?
Cape Girardeau Municipal Airport (CGI) is the main airport that has flights in and out of Southeast Missouri.
What is there to do in Southeast Missouri?
Southeast Missouri has hidden gems around every corner, but make sure you visit Johnson's Shut-ins State Park and Meramec Caverns while you're here. These landmarks shouldn't be missed.

Photos of local treasures

Browse Southeast Missouri vacation photos for more inspiration

A group of men in red uniforms with gold accents, holding rifles and wearing kilts.
A river flowing through a rocky landscape with dense green forest in the background.
A rocky river with clear water flowing over rocks.
A rocky shoreline with a calm lake and distant islands.
A river running through a forested landscape with a dirt road parallel to the river.

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